Prescription Only Medication (POM)
Ovestin cream 1mg is applied inside the vagina and contains oestrogen. It is a hormone replacement therapy (HRT) used to help relieve menopause symptoms.
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Ovestin Cream belongs to a group of medicines called Hormone Replacement Therapy (HRT). It is the branded version of the generic medication called estriol.
Ovestin is licensed by the MHRA (Medicines and Healthcare products Regulatory Agency) in the UK for the treatment of postmenopausal vaginal or urogenital atrophy.
Ovestin Cream works by replacing the oestrogen which is normally produced in the ovaries of women. It is inserted into your vagina, so the hormone is released where it is needed. This relieves the symptoms of Urogenital Atrophy.
Once you have started using estriol Ovestin Cream, you should have regular check-ups with your doctor to discuss whether it is right to continue with the treatment.
Ovestin Cream can cause side effects which are mentioned in the patient information leaflet, although not everybody gets them.
The following diseases are reported more often in women using HRT which circulate in the blood compared to women not using HRT. However, these risks apply less to vaginally administered treatments, such as Ovestin Cream:
ovarian cancer
blood clots in the veins of the legs or lungs
stroke
probable memory loss (if started over the age of 65)
You should see your doctor straight away if you notice any of the following serious side effects, as the use of Ovestin Cream may have to be stopped:
your blood pressure rises
your skin or the whites of your eyes go yellow
you suddenly have migraine-type headaches
you have signs of a blood clot
you get signs of an allergic reaction (swollen face, tongue and/or throat and/or difficulty swallowing or hives, together with difficulty breathing)
Other side effects you may experience with Ovestin Cream include:
irritation or itching of the skin in or around your vagina when you start to use this medicine
increased vaginal discharge, bleeding or spotting
gall bladder problems
skin problems such as a rash or allergy to the sun
breasts become swollen, tender or painful
headaches
feeling sick or being sick
flu-like symptoms
If you have any of these side effects tell your doctor as they may decide to stop your treatment for a while.
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