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Differin Gel
Prescription Only Medication (POM)
Differin is a topical treatment used for mild to moderate acne. It is in the class of medication known as retinoids.

Order in
for same day dispatch
Prescription Only Medication (POM)
Differin is a topical treatment used for mild to moderate acne. It is in the class of medication known as retinoids.
The active ingredient in Differin is called Adapalene. Differin has an anti-inflammatory effect reducing soreness and irritation. You can buy Differin Gel to treat mild to moderate acne on the face, chest, or back for acne, where the skin may have lots of blackheads, spots, and pimples.
Differin increases the turnover of skin cells keeping pores clear. As acne spots and pimples are often caused by pore blockages getting infected, Differin reduces the occurrence of spots and pimples.
Differin Gel can take up to four to six weeks before you see noticeable results. It should NOT be used for more than 3 months consecutively. The effectiveness of the treatment can vary from patient to patient. If you don’t feel like Differin is working for you after six weeks, speak to your healthcare professional about alternatives.
Whenever you buy Differin Gel online, or from your local GP, always use the medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
All medicines have the potential to cause side effects. The most common side effects of Differin:
These typically go away with use as your skin becomes accustomed to the medication. Uncommon side effects of Differin include:
You can find out more about Differin Gel online in the Differin Gel patient information leaflet.
Acne is a common skin condition that affects most people at some point. It causes spots, oily skin, and sometimes skin that’s hot or painful to touch. Acne commonly develops on the face, chest, and back. Acne is commonly linked to a change in hormone levels which can happen in puberty and menstrual cycles, as well as to genetic factors.
There is not always a known cause for Acne, but it is very common and affects around 95% of people aged 11-30 to some extent. For mild to moderate Acne often a pharmacist will be able to offer you creams and treatments that can help reduce acne pimples.
Other information on the causes of acne can be read about on the NHS website.
Before you buy Differin Gel online please read the ways that are recommended to prevent acne flare-ups:
Due to the recent complications of the coronavirus, it is possible your acne might be flaring up. Read our blog article; ‘Acne in quarantine: 7 reasons your skin is breaking out at home’ to learn more.
Alcohol dries out the skin so it is best to limit intake when you buy Differin Gel and commence the course of treatment.
If you buy Differin Gel it will not interact with any drugs.
Do not use Differin Gel:
If you choose to buy Differin gel online from e-Surgery, one of our prescribers will make sure the medication is suitable for you to use.
When you buy Differin Gel it will act as an anti-inflammatory decreasing the appearance of acne on the skin. Acne can decrease self-confidence so when you buy Differin Gel online, or from your local GP, it can improve this! It is important to remember,
Yes, you can legally buy Differin Gel online from registered online prescribers such as e-Surgery.
Whenever you buy Differin Gel or any other medication, make sure you check for the green GPhC logo on the bottom of each page of the website you are using.
You can use the GPhC website to check if a pharmacy is registered, this will ensure that when you buy Differin Gel online it will be genuine.
You can learn more about this Differin Gel online in the Patient Information Leaflet, which contains more useful information.
You can also use our completely free Ask-a-Pharmacist service to get health advice from a trained professional. We’re here to help!
If you choose to buy Differin Gel online from e-Surgery prices start at £24.95. This includes the cost of private prescription.
Do not store Differin above 25°C and do not freeze. Store the closed Differin tube away from direct heat as per instruction of the patient information leaflet.
Do not use Differin after the expiry date which is stated on the tube and carton. Whenever you buy Differin Gel online, or any other medication, please check the expiry date when it arrives to you in the post.
e-Surgery uses Royal Mail delivery with choices starting from; Royal Mail 48 tracked delivery, Royal Mail tracked 24 and Royal Mail 1 pm special delivery. (discover more about e-Surgery delivery). When you buy Differin Gel it will arrive in discreet, recyclable packaging at a delivery address of your choice.
Find out more if you are unsure how to recycle our packaging.