Prescription Only Medication (POM)
Please select the product variation first.
Duloxetine Capsules are used to treat depression. It works by increasing serotonin and norepinephrine levels to help regulate mood and reduce pain signals.
Duloxetine is used to treat depression. It belongs to a group of medicines known as serotonin and noradrenaline reuptake inhibitors (SNRIs). By helping to regulate certain chemicals in the brain, Duloxetine can improve mood, reduce anxiety symptoms and relieve certain types of long-term pain.
Have a question? We're here to help
Duloxetine starts to work in most people with depression or anxiety within two weeks of starting treatment, but it may take 2-4 weeks before you feel better. Tell your doctor if you do not start to feel better after this time.
You should call your doctor or pharmacist immediately if you take more than the prescribed amount. Symptoms of overdose include sleepiness, coma, serotonin syndrome, fits, vomiting and fast heart rate.
If you miss a dose, take it as soon as you remember. However, if it is time for your next dose, skip the missed dose and only take a single dose as usual. Do not take a double dose to make up for the forgotten dose.
Yes, Duloxetine can cause insomnia in some people. Difficulty sleeping is a recognised side effect, particularly during the first few weeks of treatment while your body adjusts to the medication.
Some patients may also experience vivid dreams, restlessness, or feeling more alert than usual. Taking duloxetine earlier in the day may help reduce sleep problems. If insomnia continues or becomes severe, you should speak to your healthcare provider.
Weight changes can occur while taking Duloxetine, although they are not experienced by everyone. Some people may notice a slight decrease in appetite initially, while others may experience weight gain with longer-term use.
Duloxetine should not usually be taken with other antidepressants, particularly monoamine oxidase inhibitors (MAOIs) or certain SSRIs, due to the risk of serotonin syndrome. Always inform your healthcare provider about any other medications before starting Duloxetine to avoid potentially serious interactions.
The best time to take Duloxetine depends on how it affects you. Many people take it in the morning because duloxetine can sometimes cause insomnia or increased alertness. However, if it makes you feel sleepy, your doctor may advise taking it in the evening.
You should take duloxetine at the same time each day, with or without food, to help maintain consistent levels of the medication in your body.
Duloxetine is not considered addictive in the same way as opioid painkillers or benzodiazepines. It does not usually cause cravings or compulsive use. However, stopping duloxetine suddenly can lead to withdrawal symptoms such as dizziness, nausea, headaches, anxiety, or flu-like symptoms.
If you require any additional information about Duloxetine, there are plenty of reputable sources available, such as the BNF.
The common side effects of Duloxetine include nausea, dry mouth, drowsiness, dizziness, constipation, and increased sweating. Some people may also experience changes in appetite or sleep patterns. In rare cases, Duloxetine can increase blood pressure or cause mood changes.
Duloxetine works by increasing levels of serotonin and noradrenaline in the brain. These neurotransmitters help regulate mood and pain signals. By preventing their reabsorption, the medication enhances communication between nerve cells.
e-Surgery uses Royal Mail for delivery, with choices of Royal Mail 48 Tracked, Royal Mail 24 Tracked, and Royal Mail Special Delivery by 1pm (read more here). Your medication will be delivered in discreet and recyclable packaging.
The active ingredient in Duloxetine is duloxetine hydrochloride. Duloxetine capsules also contain inactive ingredients such as gelatin, sucrose, and other capsule components that help protect the medicine until it reaches the digestive system
You should not take Duloxetine if you:
A full list of warnings and precautions can be found in the patient information leaflet.
Same day dispatch:
0 minutes