Amitriptyline works on the central nervous system to increase certain chemicals in the brain, which can alleviate pain. Amitriptyline is commonly used in the management of neuropathic pain, migraine prophylaxis and chronic tension-type headache prophylaxis.
Please note: This treatment is only for the management of neuropathic pain.
*Our price checker is only to be used as a reference of our price for this medication. If you are approved by our prescribers, they will decide on a suitable treatment for you to jointly consider.
Amitriptyline tablets belong to a class of medications known as tricyclic antidepressants. Although they are sometimes used as antidepressant they have a large variety of uses. Amitriptyline is a medicine used for treating pain.
Amitriptyline tablets work as a migraine prophylactic, meaning it is taken everyday to prevent migraines from happening. It does this by ‘increasing the levels of neurotransmitters in the brain that affect mood and well-being’—specifically, serotonin and norepinephrine. Serotonin is involved in the regulation of blood vessels during a migraine headache, and both chemicals play a role in the processing of pain by the brain.
This makes it an effective way of managing chronic migraines. The dosage will depend on what you have been prescribed, and your doctor may increase the dosage as needed. The average starting dose is 10mg taken once a day, it is suggested to be taken in the evening. It is always best to take medication at the same time each day unless informed otherwise.
You can buy Amitriptyline tablets online from a trusted pharmacy such as e-Surgery. This will require a quick, 2 minute questionnaire and your medication can be ordered straight to your door. Whenever you buy Amitriptyline tablets online always make sure to order from a trusted, reputable source.
If you buy Amitriptyline tablets take one per day to decrease the severity and intensity of migraines. Its effectiveness will vary per person, so may take some time to work out what works best for you.
Take 1 Amitriptyline tablet with water in the evening as it can cause drowsiness.
Extra side effects can occur if you suddenly stop taking Amitriptyline tablets, and it can take up to 6 weeks to take effect.
Amitriptyline tablets can take a few weeks to get into your system and to feel the pain killer effects. You can take painkillers such as paracetamol, aspirin and ibuprofen when taking Amitriptyline tablets, but it is best to avoid opiate based painkillers such as co-codamol as they can increase side effects such as drowsiness.
If you buy Amitriptyline tablets online, or from your local pharmacy, and find they are not working effectively, there are many other options of migraine medication so you may just need to find the right one.
A migraine is usually a moderate or severe headache felt as a throbbing pain on 1 side of the head.
Many people also have symptoms such as feeling sick, being sick and increased sensitivity to light or sound.
Migraine is a common health condition, affecting around 1 in every 5 women and around 1 in every 15 men. They usually begin in early adulthood.
There are several types of migraine, including:
migraine with aura – where there are specific warning signs just before the migraine begins, such as seeing flashing lights
migraine without aura – the most common type, where the migraine happens without the specific warning signs
migraine aura without headache, also known as silent migraine – where an aura or other migraine symptoms are experienced, but a headache does not develop
Some people have migraines frequently, up to several times a week. Other people only have a migraine occasionally. It’s possible for years to pass between migraine attacks. You can learn about home remedies for migraines on our blog!
The main symptom of a migraine is usually an intense headache on 1 side of the head.
The pain is usually a moderate or severe throbbing sensation that gets worse when you move and prevents you from carrying out normal activities.
In some cases, the pain can occur on both sides of your head and may affect your face or neck.
Other symptoms commonly associated with a migraine include:
feeling sick
being sick
increased sensitivity to light and sound, which is why many people with a migraine want to rest in a quiet, dark room
Some people also occasionally experience other symptoms, including:
sweating
poor concentration,
feeling very hot or very cold
tummy (abdominal) pain
diarrhoea
Not everyone with a migraine experiences these additional symptoms and some people may experience them without having a headache. The symptoms of a migraine usually last between 4 hours and 3 days, although you may feel very tired for up to a week afterwards.
The exact cause of migraines is unknown, although they’re thought to be the result of temporary changes in the chemicals, nerves and blood vessels in the brain. Around half of all people who experience migraines also have a close relative with the condition, suggesting that genes may play a role.
Some people find migraine attacks are associated with certain triggers, which can include:
starting their period
stress
tiredness
certain foods or drinks
The Patient info website has a useful article titled ‘How to figure out your migraine triggers’ that you may find effective in understanding the cause of your migraines.
Like any medication, when you buy Amitriptyline tablets online, or from your local GP, they may have side effects. Please read the patient information leaflet before you buy Amitriptyline tablets online to understand the symptoms and precautions of the mediation.
This medicine may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if you are affected.
Some common side effects include:
sleepiness/drowsiness
shakiness of hands or other body parts
Dizziness
Headache
irregular, hard, or rapid heartbeat
dizziness when you stand up due to low blood pressure (orthostatic hypotension)
dry mouth
Constipation
Nausea
excessive sweating
weight gain
slurred or slow speech
Aggression
congested nose.
If you experience any of the following side effects contact a doctor immediately:
Attacks of intermittent blurring of vision, rainbow vision, and eye pain.
A heart problem called “prolonged QT interval” (which is shown on your electrocardiogram, ECG).
Bad constipation, a swollen stomach, fever and vomiting.
Any yellowing of the skin and the white in the eyes (jaundice).
Bruising, bleeding, pallor or persistent sore throat and fever.
Effects on the blood could be a decrease in the number of red cells
Side effects between each person can vary, always read about medication side effects before you commence treatment with Amitriptyline tablets.
It is not advised to drink alcohol during treatment with this medicine as it might increase the sedative effect.
There is no known reaction between any food and Amitriptyline tablets.
There are quite a few medications, both prescription and over-the-counter (OTC), that may interact with Amitriptyline tablets. This is why it is very important to inform your doctor or prescriber about any medication you are on.
Some medications that are known to interact with amitriptyline include:
Monoamine oxidase (MAO) inhibitors, such as Marplan (isocarboxazid)
Nardil (phenelzine), Eldepryl (selegiline) and Parnate (tranylcypromine)
Antihistamines and medications for other cold symptoms or asthma
Tagamet (cimetidine)
Diet pills
Antabuse (disulfiram)
Ismelin (guanethidine)
Atrovent (ipratropium)
Quinidex (quinidine)
Tambocor (flecainide) or Rythmol (propafenone)
Anti-anxiety drugs, sedatives, sleeping pills, and tranquilizers
Medications for irritable bowel disease, mental illness, nausea, Parkinson’s disease, ulcers, urinary problems, and thyroid disease
Phenobarbital
Other antidepressants, such as fluoxetine (Prozac) and other selective serotonin reuptake inhibitors (SSRIs). Note that if you’ve stopped taking fluoxetine within the previous five weeks, you should tell your doctor
You should not take Amitriptyline tablets:
if you are allergic to amitriptyline or any of the other ingredients of this medicine
if you have recently had a heart attack (myocardial infarction)
if you have heart problems such as disturbances in heart rhythm which are seen on an electrocardiogram (ECG), heart block, or coronary artery disease
if you are taking medicines known as monoamine oxidase inhibitors (MAOIs)
if you have taken MAOIs within the last 14 days
if you have taken moclobemide the day before
if you have severe liver disease.
Inform your doctor or prescriber of the following:
narrow angle glaucoma (loss of vision due to abnormally high pressure in the eye)
epilepsy, a history of convulsions or fits
difficulty in passing urine
enlarged prostate
thyroid disease
bipolar disorder
Schizophrenia
severe liver disease
severe heart disease
pylorus stenosis (narrowing of the gastric outlet) and paralytic ileus (blocked intestine)
diabetes as you might need and adjustment of your antidiabetic medicine.
Migraines can be a debilitating condition that affects many areas of life. Although a singular cure has not yet been found as migraines can present very differently in each person managing symptoms is key. When you buy Amitriptyline tablets online, or from your local GP, they can help stop the migraines from happening, making them a great solution for those who suffer with consistent migraines.
Amitriptyline tablets differ slightly from some other migraine treatments. Medicines such as Sumatriptan, Rizatriptan and Zolmitriptan should be taken when the first symptoms of a migraine appear, whereas Amitriptyline should be taken once daily to prevent migraine headaches. This is beneficial for long term migraine sufferers.
There is also a small price difference between the different types of medication.
Do not use Amitriptyline tablets after the expiration date on the box. Whenever you buy Amitriptyline tablets online, or any other medication please check the expiry date when it arrives to you in the post.
You can buy Amitriptyline tablets online from registered prescribers such as e-Surgery.
Whenever you buy Amitriptyline tablets online or any other medication, make sure you check for the green GPhC and MHRA logo on the bottom of each page of the website you are using.
You can use the GPhC website to check if a pharmacy is registered. This will ensure that when you buy Amitriptyline tablets online the tablets are genuine.
You can also use our completely free Ask-a-Pharmacist service to get health advice from a trained professional. We’re here to help!
e-Surgery uses Royal Mail delivery with choices starting from Royal Mail tracked 48 delivery, Royal Mail tracked 24and Royal Mail 1pm special delivery (discover more about e-Surgery delivery). When you buy Amitriptyline tablets they will arrive in discreet, recyclable packaging at a delivery address of your choice. Find out to recycle packaging from e-Surgery.
Whenever you buy Amitriptyline tablets online they come in blister packs that are not currently recyclable, so once they have been used can be disposed of in a general waste bin. If the Amitriptyline tablets are unfinished dispose of medication safely and drop them off at a local pharmacy. Cardboard packaging and paper patient information leaflets are recyclable.
For any more information on disposal of Amitriptyline tablets you can use our free Ask-a-Pharmacist service.
8 reviews for Amitriptyline Tablets (For Neuropathic Pain)
Rated 5 out of 5
Wade –
Very good service, 100 percent legitimate. Please continue to supply this. thank you.
Rated 5 out of 5
Peter Wallace –
Lowest price online, last chemist I used was charging over 2x the price for the same exact tablets.
Rated 5 out of 5
Carl W –
Same as my local surgery. Thank you.
Rated 5 out of 5
Greg H –
Proper UK branded tablets, unlike competitors that send European boxes at twice the price.
Rated 5 out of 5
Mary –
Convenient way to get my tablets, good quality as well.
Rated 5 out of 5
Arnold Keys –
Worked as expected. Thank you.
Rated 5 out of 5
Annie –
Easy way to get the tablets I need. Very good.
Rated 5 out of 5
carolynhaineshurley –
Excellent service
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e-Surgery is UK’s leading online Prescriber & Pharmacy focused on sustainability. We are regulated by the GPhC and MHRA to provide you with a safe and simple way to order your medication online.
Wade –
Very good service, 100 percent legitimate. Please continue to supply this. thank you.
Peter Wallace –
Lowest price online, last chemist I used was charging over 2x the price for the same exact tablets.
Carl W –
Same as my local surgery. Thank you.
Greg H –
Proper UK branded tablets, unlike competitors that send European boxes at twice the price.
Mary –
Convenient way to get my tablets, good quality as well.
Arnold Keys –
Worked as expected. Thank you.
Annie –
Easy way to get the tablets I need. Very good.
carolynhaineshurley –
Excellent service