Woman holding head in pain from migraine and high blood pressure

Migraines are more than just headaches; they can be debilitating and significantly impact one’s quality of life. For many suffers, finding effective ways to prevent these painful episodes is crucial. 

This ultimate guide from e-Surgery will provide comprehensive information on migraine prophylaxis, discuss various medications, treatments, and strategies to help manage and reduce the frequency and severity of migraines. 

What Is Migraine Prophylaxis?

Migraine prophylaxis refers to the preventive treatment aimed at reducing the frequency, duration, and severity of migraine attacks. Unlike acute treatments that address symptoms once a migraine has started, prophylactic treatments are taken regularly to prevent the onset of migraines. This approach is particularly beneficial for individuals who experience frequent or severe migraine attacks that significantly impact their daily lives. 

The primary goals of migraine prophylaxis are to decrease the number of migraine days per month, making the attacks less severe when they do occur, making migraines easier to treat with acute medications, allowing individuals to participate more fully in daily activities without the constant fear of an impending migraine. 

In general, prophylactic treatment may be recommended for individuals who have: 

  • Four or more migraine days per month. 
  • Migraines that significantly interfere with daily activities. 
  • Acute migraine medications that are ineffective or cause side effects. 
  • Certain types of migraines, such as hemiplegic migraines.

Understanding Migraines

Migraines can vary widely among sufferers. The most common types include: 

  • Migraine With Aura: Characterised by sensory disturbances that precede the headache phase, such as visual changes, tingling, or speech difficulties. 
  • Migraine Without Aura: The most common type, where the migraine attack occurs without preceding sensory disturbances. 
  • Chronic Migraine: Defined as having headaches on 15 or more days per month for more than three months, with at least eight days of migraine features. 

It’s also important to be aware of the symptoms of migraines which often include throbbing or pulsating pain that is usually on one side of the head, sensitivity to light, sound or smells, nausea and vomiting, and dizziness and blurred vision. 

There are also common triggers to be aware of: 

  • Stress: Emotional stress and anxiety are significant triggers for many individuals. 
  • Hormonal Changes: Fluctuations in hormone levels can trigger migraines. 
  • Dietary Factors: Certain foods and beverages are known triggers, such as caffeine, alcohol, aged cheeses, and processed meats. 
  • Sleep Disturbances: Both too much and too little sleep can trigger migraines 
  • Environmental Factors: Bright lights, loud noises, strong smells, and changes in weather can trigger migraines. 
  • Physical Exertion: Intense physical activity or sudden, vigorous exercise can lead to migraine onset in some individuals. 
  • Medications: Certain medications, including oral contraceptives and vasodilators, can trigger migraines in some people. 

By understanding the types, symptoms, and triggers of migraines, individuals can better manage their condition and work with their doctors to develop effective treatment and prevention strategies. 

Importance Of Migraine Prophylaxis 

Migraine prophylaxis is essential for individuals who experience frequent or severe migraine attacks, as it significantly improves their quality of life. Preventive treatment aims to reduce the frequency, duration, and severity of migraines, making day-to-day living more manageable. By decreasing the number of migraine days per month, prophylaxis helps individuals avoid the debilitating impact of migraines on work, social activities, and overall well-being. 

Additionally, it lessens the reliance on acute medications, which can have adverse side effects and lead to medication overuse headaches. Effective migraine prophylaxis also enhances the responsiveness to acute treatments, making them more effective when a migraine does occur. 

Ultimately, implementing a preventive strategy enables individuals to engage more fully in their lives without the constant fear of an impending migraine, fostering better physical, emotional, and mental health. 

Medications For Migraine Prophylaxis 

There are several classes of medications used for migraine prophylaxis, each working differently to help prevent migraines. 

  • Beta-Blockers: beta-blockers such as propranolol and metoprolol are commonly used. They work by relaxing blood vessels and reducing blood pressure, which can help prevent the onset of migraines. 
  • Antidepressants: Certain antidepressants, particularly tricyclic antidepressants like amitriptyline, are effective in preventing migraines. These medications influence serotonin levels in the brain, which can help stabilize mood and reduce migraine frequency. 
  • Anticonvulsants: Medications such as topiramate and valproate, typically used to treat epilepsy, can also help prevent migraines. They work by stabilizing electrical activity in the brain. 

Selecting the appropriate prophylactic medication depends on various factors, including: the frequency and severity of migraines, other medical conditions, potential side effects, medication interactions, and patient preferences. 

It is crucial to work closely with your doctor to find the most suitable option for you. It is not a one-size-fits-all approach and requires ongoing monitoring and adjustment. Throughout your treatment you should: 

  • Keep a migraine diary to track frequency, severity, and potential triggers. 
  • Regularly communicate with their doctor about treatment effectiveness. 
  • Be patient, as it may take several weeks or months to see the full benefits of prophylactic treatment. 
  • Be prepared to try different medications or combinations if the initial treatment is not effective. 

Lifestyle Changes 

In additional to medications, various lifestyle changes can be beneficial in preventing migraines.  

  • Lifestyle Modifications: adopting a healthy lifestyle can significantly impact migraine frequency and severity. The key modifications include regular sleep patterns, hydration, and regular exercise. 
  • Dietary Changes: It’s crucial to identify and avoid certain foods and beverages that can be migraine triggers. These include caffeine, alcohol, aged cheeses, processed meats. 
  • Physical Activity: Regular exercise can help reduce the frequency of migraines by reducing stress and promoting overall well-being. However, it’s essential to avoid overexertion, which can trigger migraines in some individuals. 
  • Stress Management: Stress is a significant trigger for many migraine sufferers. Techniques such as mindfulness, meditation, and yoga can help manage stress levels effectively.  

Next Steps 

Migraine prophylaxis can be life-changing for those who suffer from frequent or severe migraines. While it may take time to find the right approach, a combination of lifestyle changes, medications, alternative therapies can significantly reduce the burden of migraines.  

Remember, the key to successful migraine prophylaxis is working closely with doctors to develop a personalised treatment plan. 

At e-Surgery, we offer a range of safe and effective migraine prophylaxis medications to help you manage your migraines with confidence. We also offer a completely free ‘Ask-a-Pharmacist‘ service where you can receive professional healthcare advice from a UK trained pharmacist. We’re here to help.