Weight loss support,planned around you

It depends on the type. Fullness-hormone medicines (for example, Mounjaro and Wegovy) slow how quickly your stomach empties and signal to your brain that you’ve had enough, so you feel full sooner. Combination tablets (for example, Mysimba) work on the parts of the brain that control hunger. Fat-absorption capsules (for example, Orlistat or Xenical) block an enzyme that breaks down fat, so some of the fat you eat passes through undigested.

Yes, you choose. At the end of the consultation you pick the treatment you’d like, at the price shown. Injections are taken once a week, hormone tablets once a day, combination tablets are usually built up to twice a day, and fat-absorption capsules are taken with each main meal. A UK prescriber then reviews your answers and only approves your choice if it’s medically suitable. If it isn’t, they’ll explain why and suggest an alternative if one is available, or refer you.

Treatment is usually suitable if you’re 18 or over and have a BMI of 30 or more, or 27 or more if you have a weight-related health condition (24.5 or more if you’re from a South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean background). Examples of these conditions include type 2 diabetes, high blood pressure, PCOS, some heart conditions, non-alcoholic fatty liver disease, chronic severe joint pain, and low testosterone in men. We may ask for proof of your condition, for example from your GP record. You’ll also need to be ready to make changes to diet and activity alongside treatment. Your prescriber makes the final decision.

Weight loss treatment isn’t suitable for everyone. You can’t have treatment if you:

• are under 18
• are pregnant or breastfeeding
• have, or are being treated for, an eating disorder
• are allergic to the medicine or any of its ingredients
• don’t meet the BMI requirement for treatment

Each medicine also has its own safety criteria, which can include certain medical conditions, a family history of some conditions, and other medicines you take. You can find the full list on each treatment’s page.

Our clinicians review your consultation answers and medical record to check that your chosen treatment is safe for you. If it isn’t, they may suggest a different option.

It can. NICE recommends a lower BMI threshold, usually 2.5 lower, for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean backgrounds, because the risk of conditions like type 2 diabetes starts at a lower BMI. Prescribing at a lower BMI for these groups is outside the medicine’s product licence, which is known as ‘off-label’ use.

Yes, when it’s prescribed properly. Every consultation is reviewed by a UK prescriber, who only approves treatment if it’s clinically appropriate. Licensed weight loss medicines have been through clinical trials and are considered safe when prescribed and monitored.

Side effects depend on the treatment. Fullness-hormone medicines most often cause nausea, diarrhoea, constipation or stomach pain, usually mild and easing over time. Fat-absorption capsules can cause oily or loose stools, especially after fatty meals. Combination tablets can cause nausea, headaches, trouble sleeping or mood changes.

Rarer, more serious side effects are possible. If you get severe stomach pain that doesn’t go away, which may spread to your back, with or without being sick, stop taking your treatment and get urgent medical help straight away by calling 999 or going to A&E. Your patient leaflet lists all possible side effects.

Tell us about every medicine you take, including the contraceptive pill.

Wegovy injection: Wegovy doesn’t affect how well the contraceptive pill works. If you have severe vomiting or diarrhoea, your pill may not be absorbed properly, so use extra contraception such as condoms until you’re well.

Wegovy tablets: Wegovy tablets don’t affect how well the contraceptive pill works. If you have severe vomiting or diarrhoea, your pill may not be absorbed properly, so use extra contraception such as condoms until you’re well. Wait 30 minutes after your Wegovy tablet before taking any other tablets.

Mounjaro: Mounjaro can make the contraceptive pill less effective. If you take the pill, switch to a non-oral method (such as a coil, implant or injection) or also use condoms for 4 weeks after starting Mounjaro and for 4 weeks after each dose increase.

Foundayo: Foundayo can make the contraceptive pill less effective. If you take the pill, switch to a non-oral method (such as a coil, implant or injection) or also use condoms for 30 days after starting Foundayo and for 30 days after each dose increase.

Xenical (orlistat): Xenical doesn’t directly affect the contraceptive pill. If you have severe diarrhoea, your pill may not be absorbed properly, so use extra contraception such as condoms if this happens.

Mysimba: Mysimba isn’t known to affect hormonal contraception. You shouldn’t take it if you’re pregnant or trying to get pregnant.

Many people notice a change in appetite within the first few weeks. How much weight changes, and how quickly, varies from person to person and depends on the treatment, your dose and the changes you make to diet and activity.

Results vary from person to person. In clinical trials, people taking these medicines alongside a reduced-calorie diet and more activity lost, on average:

• Mounjaro: 22.5% of body weight at the 15mg dose over 72 weeks (SURMOUNT-1, NEJM 2022)
• Wegovy injection: 20.7% at the 7.2mg dose over 72 weeks (STEP UP, Lancet Diabetes & Endocrinology 2025), or 14.9% at 2.4mg over 68 weeks (STEP 1, NEJM 2021)
• Wegovy tablet: about 14% at 25mg over 64 weeks, compared with 2.4% on placebo (OASIS 4, NEJM 2025)
• Foundayo: 12.4% at the top dose over 72 weeks (ATTAIN-1, NEJM 2025)
• Mysimba: 3.7–5.7% over 28–56 weeks, compared with 1.3–1.9% on placebo, across three trials (COR-I, COR-II and COR-DM; COR-I, Lancet 2010)
• Orlistat / Xenical: an average of 11.4kg after 1 year, compared with 7.5kg with lifestyle changes alone (XENDOS, Diabetes Care 2004)

These are averages from clinical trials; your results may be different. Your prescriber can talk you through what’s realistic for you.

Some weight may come back, as the medicine’s effect on appetite or fat absorption stops. These medicines are usually taken long-term, and keeping up the changes you’ve made to diet and activity gives you the best chance of keeping weight off. Talk to us before stopping.

It’s a short online questionnaire about your health, weight and current medicines. It takes under 2 minutes and is free. At the end you choose your treatment and see the price before you pay. A UK prescriber then reviews your order.

Prices depend on the treatment and dose and are shown on each product before you pay. There are no consultation fees.

Once your prescription is approved, we send it with next day delivery in plain, fully recyclable packaging.

Yes. You can ask to change your dose or switch to a different medicine when you place your next order. A prescriber reviews every request to make sure the change is safe for you.

Changing your dose: You can move up one dose step per order, once you’ve been on your current dose for the minimum time (usually 4 weeks or a month, depending on your medicine). If you’re having side effects, you can choose a lower dose. If you have a subscription, a lower dose isn’t selected automatically, so choose it when you order.

Switching medicine: Your new dose is based on the medicine and dose you take now. If you’re not getting your current treatment from us, we may ask for proof of it. We’ll tell you when to take your first dose of the new medicine. Never take two weight loss medicines at the same time.

Taking a break: If you stop for 3 months or more, you’ll restart on the starting dose. After a shorter break, you may need a lower dose to restart, depending on your medicine. Tell us about any break when you reorder.

This applies only if you use an injectable medicine, such as Wegovy injection or Mounjaro.

Put used needles in a sharps bin. You can add one to your order. A sharps bin keeps your household and waste collectors safe from needle injuries.

When your sharps bin is full, contact your local council to find out how to arrange collection or disposal in your area. Don’t put sharps bins or loose needles in your general household waste without checking with your council first.

Use our “My pen is not working” support page, chat with us, or call 01603 931 600 and our team will help.

Some people can get weight loss treatment on the NHS, through their GP or a specialist weight management service. Who’s eligible, which treatments are offered and how long you’ll wait depend on NHS guidelines and on what’s available in your area. Your GP can tell you what support you might be able to get locally.

Getting treatment online can be more convenient. You can complete your consultation and order whenever suits you, without having to fit around appointment times. If you choose private treatment online, make sure you use a UK pharmacy registered with the General Pharmaceutical Council (GPhC).